Across TCGA pan-cancer cohorts, PGPEP1L Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated PGPEP1L data layer compared with 22 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PGPEP1L Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PGPEP1L expression acts as an unfavorable survival marker.

KIRC are the cancer types where PGPEP1L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	II,III,IV	0.181	0.696	.042	9	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: PGPEP1L tumor-vs-normal RNA expression · all PGPEP1L data types