PGPEP1

Across TCGA patient cohorts, PGPEP1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,127 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PGPEP1-associated genes across cancer lineages are FAM72B, NCAPG, and GDF15. Each is linked with PGPEP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PGPEP1-to-partner and partner-to-PGPEP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGPEP1 versus FAM72B in BRCA, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGPEP1→partner) and Y-score (partner→PGPEP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FAM72B →	-0.871	-0.533	<.001	<.001	3	6
BRCA	NCAPG →	-1.054	-0.515	<.001	<.001	3	5
LUAD	GDF15 →	+1.108	+0.213	.001	.003	3	5
BRCA	DSCC1 →	-0.763	-0.467	<.001	<.001	3	5
BRCA	CEP55 →	-0.981	-0.469	<.001	.001	3	5
BRCA	CCNA2 →	-1.041	-0.555	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,127 associations by consensus.

PGPEP1 vs FAM72B — BRCA

Explore this scatter interactively →