Across TCGA patient cohorts, PGP RNA expression is significantly associated with the protein abundance of many other proteins, with 16,467 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PGP-associated proteins across cancer lineages are NASP, RFC2, and RRM2. Each is linked with PGP in more than 7 cancer types. Because this analysis shows association rather than direction, both PGP-to-partner and partner-to-PGP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PGP→partner) and Y-score (partner→PGP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NASP →	+0.516	+0.712	.001	.001	2	8
LSCC	RFC2 →	+0.455	+0.476	<.001	<.001	3	6
UCEC	RRM2 →	+0.642	+0.795	<.001	<.001	3	6
OV	DTL_S478 →	+0.902	+0.555	.003	.005	3	6
LUAD	ECT2_T359 →	+1.154	+0.415	<.001	<.001	3	6
LSCC	MCM2 →	+0.606	+0.446	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,467 associations by consensus.

Exploration

PGP survival (RNA) · tumor vs normal (RNA) · all PGP data types