Across TCGA cell cohorts, PGP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,249 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible PGP-associated GO terms across cancer lineages are Mitotic DNA replication, DNA strand elongation involved in DNA replication, and Leading strand elongation. Each is linked with PGP in more than 15 cancer types. Because this analysis shows association rather than direction, both PGP-to-partner and partner-to-PGP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGP→partner) and Y-score (partner→PGP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Mitotic DNA replication →	+0.146	+0.660	<.001	.001	3	16
SOFT_TISSUE	DNA strand elongation involved in DNA replication →	+0.174	+0.754	<.001	<.001	3	16
SOFT_TISSUE	Leading strand elongation →	+0.171	+0.863	<.001	<.001	3	16
LARGE_INTESTINE	Regulation of DNA-templated DNA replication →	+0.086	+0.647	<.001	<.001	3	16
LIVER	Cell cycle DNA replication →	+0.133	+0.878	<.001	<.001	3	15
BLOOD_Myeloma	DNA-templated DNA replication maintenance of fidelity →	+0.113	+1.132	.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,249 associations by consensus.

Exploration

PGP survival (RNA) · tumor vs normal (RNA) · all PGP data types