Across TCGA pan-cancer cohorts, PGM5P4 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated PGM5P4 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher PGM5P4 RNA is associated with better overall survival. In most high-consensus cancer types, elevated PGM5P4 expression acts as an unfavorable survival marker, although some lineages such as BRCA and MESO show a favorable association.

BRCA, MESO, and UCS are the cancer types where PGM5P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Tertile	III,IV	0.936	0.738	<.001	59	view →
MESO	DFS	Median	All	0.443	0.285	.002	58	view →
UCS	DFS	Tertile	II,III,IV	0.623	0.123	.001	36	view →
LUAD	OS	Tertile	All	0.872	0.768	.006	31	view →
ACC	OS	Quartile	II,III,IV	0.192	0.722	.013	28	view →
COAD	DFS	Median	II,III,IV	0.538	0.715	.008	27	view →
PAAD	DFS	Quartile	II,III,IV	0.453	0.254	.002	21	view →
UVM	DFS	Tertile	All	0.394	0.894	<.001	20	view →
KIRC	DFS	Quartile	All	0.864	0.722	.016	16	view →
DLBC	OS	Median	II,III,IV	1.000	0.521	.016	15	view →
SKCM	OS	Median	IV	0.728	0.181	.013	10	view →
SARC	DFS	Quartile	All	0.741	0.460	.008	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

Exploration

Same gene, other analysis: PGM5P4 tumor-vs-normal RNA expression · all PGM5P4 data types