PGM5

Across TCGA cell cohorts, PGM5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,116 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PGM5-associated GO terms across cancer lineages are Nucleoside triphosphate biosynthetic process, Protein insertion into membrane, and Spliceosomal conformational changes to generate catalytic conformation. Each is linked with PGM5 in more than 5 cancer types. Because this analysis shows association rather than direction, both PGM5-to-partner and partner-to-PGM5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside triphosphate biosynthetic process grouped by PGM5-low versus PGM5-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGM5→partner) and Y-score (partner→PGM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Nucleoside triphosphate biosynthetic process →	+0.042	+0.849	<.001	.009	3	6
SKIN	Protein insertion into membrane →	+0.049	+0.995	.002	<.001	3	6
SOFT_TISSUE	Spliceosomal conformational changes to generate catalytic conformation →	+0.063	+1.760	<.001	<.001	3	6
KIDNEY	Cellular respiration →	+0.044	+0.197	.004	.005	2	6
SOFT_TISSUE	NMDA selective glutamate receptor signaling pathway →	-0.144	-1.491	<.001	.001	3	5
BREAST	Positive regulation of gene expression, epigenetic →	+0.058	+1.336	.003	.003	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,116 associations by consensus.

Nucleoside triphosphate biosynthetic process by PGM5 expression — CNS

Explore this box plot interactively →