PGM3

Across TCGA pan-cancer cohorts, PGM3 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PGM3 data layer compared with 30 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PGM3 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PGM3 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, CCRCC, and LUAD are the cancer types where PGM3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	All	1.000	0.786	.007	18	view →
CCRCC	DFS	Median	All	0.613	0.863	.001	17	view →
LUAD	OS	Median	II,III,IV	0.455	0.765	.010	13	view →
LSCC	DFS	Median	All	1.000	0.597	.006	7	view →
PDAC	DFS	Tertile	IV	0.199	0.752	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PGM3–UCEC (DFS)

Open the UCEC breakdown →