PGM3

Across TCGA patient cohorts, PGM3 mutation is significantly associated with the RNA expression of many other genes, with 3,475 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PGM3-associated genes across cancer lineages are RNU6-1082P, HSPD1P18, and RNU6-618P. Each is linked with PGM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PGM3-to-partner and partner-to-PGM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1082P grouped by PGM3-low versus PGM3-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGM3→partner) and Y-score (partner→PGM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNU6-1082P →	+0.382	+6.108	<.001	<.001	3	2
LIHC	HSPD1P18 →	+0.113	+5.232	<.001	<.001	3	2
SKCM	RNU6-618P →	+0.339	+3.767	<.001	.003	3	2
BLCA	MRPL51P2 →	+0.114	+7.640	<.001	.009	3	2
READ	RN7SL783P →	+0.277	+5.653	<.001	.003	3	2
UCEC	EIF3JP1 →	+0.193	+1.912	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,475 associations by consensus.

RNU6-1082P by PGM3 expression — LIHC

Explore this box plot interactively →