PGM3

Across TCGA cell cohorts, PGM3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,247 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PGM3-associated GO terms across cancer lineages are Positive regulation of protein exit from endoplasmic reticulum, COPII-coated vesicle cargo loading, and SRP-dependent cotranslational protein targeting to membrane. Each is linked with PGM3 in more than 16 cancer types. Because this analysis shows association rather than direction, both PGM3-to-partner and partner-to-PGM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein exit from endoplasmic reticulum grouped by PGM3-low versus PGM3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGM3→partner) and Y-score (partner→PGM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of protein exit from endoplasmic reticulum →	+0.176	+0.985	<.001	<.001	3	17
BONE	COPII-coated vesicle cargo loading →	+0.140	+0.821	<.001	<.001	3	15
LIVER	SRP-dependent cotranslational protein targeting to membrane →	+0.127	+1.477	.001	<.001	3	15
BONE	Regulation of protein exit from endoplasmic reticulum →	+0.163	+0.793	<.001	<.001	3	15
OVARY	7-methylguanosine RNA capping →	+0.111	+0.694	.001	.002	3	13
OVARY	7-methylguanosine mRNA capping →	+0.111	+0.694	.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,247 associations by consensus.

Positive regulation of protein exit from endoplasmic reticulum by PGM3 expression — BONE

Explore this box plot interactively →