PGM2

Across TCGA patient cohorts, PGM2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,343 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PGM2-associated genes across cancer lineages are KIF20A, KIF18B, and MYBL2. Each is linked with PGM2 in more than 8 cancer types. Because this analysis shows association rather than direction, both PGM2-to-partner and partner-to-PGM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGM2 versus KIF20A in UCEC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGM2→partner) and Y-score (partner→PGM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIF20A →	-1.069	-0.288	<.001	<.001	3	9
BRCA	KIF18B →	-0.831	-0.225	<.001	<.001	3	9
GBM	MYBL2 →	-1.205	-0.231	.002	.001	3	8
GBM	CENPF →	-0.993	-0.216	.008	<.001	3	8
GBM	HJURP →	-0.977	-0.195	.002	.001	3	8
GBM	PIMREG →	-1.037	-0.207	.005	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,343 associations by consensus.

PGM2 vs KIF20A — UCEC

Explore this scatter interactively →