PGLYRP4

Across TCGA patient cohorts, PGLYRP4 protein abundance is significantly associated with the RNA expression of many other genes, with 4,662 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PGLYRP4-associated genes across cancer lineages are SNRPD3, SLC35E4, and CCDC134. Each is linked with PGLYRP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PGLYRP4-to-partner and partner-to-PGLYRP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGLYRP4 versus SNRPD3 in HNSC, with a Pearson correlation of -0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGLYRP4→partner) and Y-score (partner→PGLYRP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SNRPD3 →	-0.739	-0.971	.003	.002	3	1
HNSC	SLC35E4 →	+0.580	+0.897	.004	.002	3	1
HNSC	CCDC134 →	-0.700	-1.090	.005	.001	3	1
HNSC	DEPDC5 →	-0.568	-0.989	.004	.001	3	1
HNSC	TTC28 →	-0.948	-1.046	<.001	<.001	3	1
HNSC	RANBP9 →	-0.514	-0.843	.004	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,662 associations by consensus.

PGLYRP4 vs SNRPD3 — HNSC

Explore this scatter interactively →