PGLYRP4

Across TCGA patient cohorts, PGLYRP4 mutation is significantly associated with the RNA expression of many other genes, with 1,577 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PGLYRP4-associated genes across cancer lineages are CDY11P, UBE2V1P8, and RNU6-1152P. Each is linked with PGLYRP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both PGLYRP4-to-partner and partner-to-PGLYRP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDY11P grouped by PGLYRP4-low versus PGLYRP4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGLYRP4→partner) and Y-score (partner→PGLYRP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CDY11P →	+0.005	+2.934	<.001	.006	3	3
LGG	UBE2V1P8 →	+0.144	+6.155	<.001	<.001	3	2
LIHC	RNU6-1152P →	+0.352	+5.305	<.001	.003	3	2
LIHC	TBC1D3P7 →	+0.072	+5.676	<.001	.001	3	2
LIHC	SUGT1P4 →	+0.290	+4.878	<.001	.005	3	2
UCEC	HIRIP3 →	+0.438	+3.732	.005	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,577 associations by consensus.

CDY11P by PGLYRP4 expression — SKCM

Explore this box plot interactively →