PGLYRP4

Across TCGA cell cohorts, PGLYRP4 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. CNS shows the largest number of these associations.

The most reproducible PGLYRP4-associated genes across cancer lineages are TEX55, OR11H6, and FGF3. Each is linked with PGLYRP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PGLYRP4-to-partner and partner-to-PGLYRP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX55 grouped by PGLYRP4-low versus PGLYRP4-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGLYRP4→partner) and Y-score (partner→PGLYRP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	TEX55 →	+0.049	+5.321	<.001	.005	3	1
CNS	OR11H6 →	+0.021	+5.321	<.001	.005	3	1
CNS	FGF3 →	+0.040	+4.981	.001	.008	3	1
CNS	MEIKIN →	+0.093	+5.321	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

TEX55 by PGLYRP4 expression — CNS

Explore this box plot interactively →