PGLYRP3

Across TCGA patient cohorts, PGLYRP3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,188 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PGLYRP3-associated genes across cancer lineages are SLC5A1, CBX7, and GRAP2. Each is linked with PGLYRP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PGLYRP3-to-partner and partner-to-PGLYRP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGLYRP3 versus SLC5A1 in HNSC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGLYRP3→partner) and Y-score (partner→PGLYRP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SLC5A1 →	+1.341	+0.830	.003	.004	3	1
HNSC	CBX7 →	-0.719	-1.036	<.001	<.001	3	1
HNSC	GRAP2 →	-0.986	-1.180	.001	<.001	3	1
HNSC	IFT27 →	-0.746	-0.956	.002	.008	3	1
HNSC	COCH →	-1.113	-1.024	.002	.001	3	1
HNSC	DDHD1 →	-0.780	-1.198	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,188 associations by consensus.

PGLYRP3 vs SLC5A1 — HNSC

Explore this scatter interactively →