PGLYRP3

Across TCGA cell cohorts, PGLYRP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 732 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PGLYRP3-associated GO terms across cancer lineages are Intermediate filament-based process, Intermediate filament cytoskeleton organization, and NMDA selective glutamate receptor signaling pathway. Each is linked with PGLYRP3 in more than 5 cancer types. Because this analysis shows association rather than direction, both PGLYRP3-to-partner and partner-to-PGLYRP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intermediate filament-based process grouped by PGLYRP3-low versus PGLYRP3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGLYRP3→partner) and Y-score (partner→PGLYRP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Intermediate filament-based process →	+0.106	+1.228	<.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Intermediate filament cytoskeleton organization →	+0.106	+1.297	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	NMDA selective glutamate receptor signaling pathway →	+0.173	+1.887	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Glycerol transmembrane transport →	+0.899	+1.036	.001	.006	3	5
UPPER_AERODIGESTIVE_TRACT	Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.089	+1.397	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	Lipoxygenase pathway →	-0.314	-2.071	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 732 associations by consensus.

Intermediate filament-based process by PGLYRP3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →