PGLYRP2

Across TCGA patient cohorts, PGLYRP2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,860 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PGLYRP2-associated genes across cancer lineages are LTBP2, RHOJ, and GFPT2. Each is linked with PGLYRP2 in more than 6 cancer types. Because this analysis shows association rather than direction, both PGLYRP2-to-partner and partner-to-PGLYRP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGLYRP2 versus LTBP2 in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGLYRP2→partner) and Y-score (partner→PGLYRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LTBP2 →	+0.942	+0.430	<.001	<.001	3	7
BRCA	RHOJ →	+0.778	+0.458	<.001	<.001	3	7
COAD	GFPT2 →	+1.160	+0.387	<.001	<.001	3	7
COAD	AOC3 →	+1.125	+0.421	<.001	<.001	3	7
COAD	FLI1 →	+0.564	+0.351	<.001	.001	3	7
HNSC	OLFML2B →	+0.984	+0.319	<.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,860 associations by consensus.

PGLYRP2 vs LTBP2 — GBM

Explore this scatter interactively →