PGLYRP2

Across TCGA cell cohorts, PGLYRP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,189 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PGLYRP2-associated GO terms across cancer lineages are Regulation of microtubule polymerization, Chromosomal 5-methylcytosine DNA demethylation pathway, and Cholesterol biosynthetic process via lathosterol. Each is linked with PGLYRP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PGLYRP2-to-partner and partner-to-PGLYRP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of microtubule polymerization grouped by PGLYRP2-low versus PGLYRP2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGLYRP2→partner) and Y-score (partner→PGLYRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of microtubule polymerization →	+0.057	+0.092	<.001	.002	3	5
BREAST	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.107	+1.311	<.001	.001	3	5
BONE	Cholesterol biosynthetic process via lathosterol →	+0.219	+1.241	<.001	<.001	3	5
BREAST	Extracellular matrix assembly →	-0.134	-0.816	.007	.005	3	4
BONE	Positive regulation of steroid hormone secretion →	-1.577	-2.038	<.001	<.001	3	4
BONE	Rostrocaudal neural tube patterning →	+0.196	+1.520	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,189 associations by consensus.

Regulation of microtubule polymerization by PGLYRP2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →