PGLYRP1

Across TCGA pan-cancer cohorts, PGLYRP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated PGLYRP1 data layer compared with 21 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PGLYRP1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated PGLYRP1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and CCRCC show a favorable association.

UCEC, LUAD, and CCRCC are the cancer types where PGLYRP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	1.000	0.433	.007	24	view →
LUAD	OS	Median	III,IV	0.325	0.824	.002	15	view →
CCRCC	OS	Median	IV	0.785	0.123	.009	6	view →
HNSC	OS	Quartile	All	0.814	0.577	.020	6	view →
PDAC	DFS	Quartile	All	0.326	0.529	.019	6	view →
LSCC	DFS	Tertile	All	0.754	0.408	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

PGLYRP1–UCEC (OS)

Open the UCEC breakdown →