PGK1

Across TCGA cell cohorts, PGK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,291 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PGK1-associated GO terms across cancer lineages are Purine nucleoside diphosphate catabolic process, Purine ribonucleoside diphosphate catabolic process, and Hypoxia-inducible factor-1alpha signaling pathway. Each is linked with PGK1 in more than 14 cancer types. Because this analysis shows association rather than direction, both PGK1-to-partner and partner-to-PGK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine nucleoside diphosphate catabolic process grouped by PGK1-low versus PGK1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGK1→partner) and Y-score (partner→PGK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Purine nucleoside diphosphate catabolic process →	+0.110	+0.829	<.001	<.001	3	15
SKIN	Purine ribonucleoside diphosphate catabolic process →	+0.110	+0.829	<.001	<.001	3	15
CNS	Hypoxia-inducible factor-1alpha signaling pathway →	+1.133	+0.997	<.001	<.001	3	15
OVARY	Glycolytic process through fructose-6-phosphate →	+0.121	+0.924	<.001	.001	3	14
OVARY	Glycolytic process through glucose-6-phosphate →	+0.121	+0.924	<.001	.001	3	14
URINARY_TRACT	Ribonucleoside diphosphate catabolic process →	+0.113	+1.124	.002	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,291 associations by consensus.

Purine nucleoside diphosphate catabolic process by PGK1 expression — SKIN

Explore this box plot interactively →