PGGHG

Across TCGA patient cohorts, PGGHG protein abundance is significantly associated with the protein abundance of many other proteins, with 14,844 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PGGHG-associated proteins across cancer lineages are C11orf96_S399, AFG3L2, and SNX9. Each is linked with PGGHG in more than 3 cancer types. Because this analysis shows association rather than direction, both PGGHG-to-partner and partner-to-PGGHG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGGHG versus C11orf96_S399 in HNSC, with a Pearson correlation of 0.34.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PGGHG→partner) and Y-score (partner→PGGHG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	C11orf96_S399 →	+0.773	+0.255	<.001	<.001	3	4
LSCC	AFG3L2 →	-0.409	-0.259	<.001	<.001	3	4
GBM	SNX9 →	+0.401	+0.456	<.001	<.001	3	4
LSCC	STRBP →	-0.466	-0.181	<.001	<.001	3	4
GBM	TBC1D2B →	+0.403	+0.420	<.001	<.001	3	4
GBM	TNIP2 →	+0.336	+0.316	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,844 associations by consensus.

PGGHG vs C11orf96_S399 — HNSC

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