PGGHG

Across TCGA cell cohorts, PGGHG RNA expression is significantly associated with the go_rna of many other GO terms, with 4,224 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PGGHG-associated GO terms across cancer lineages are Protein polyglycylation, Pre-mRNA catabolic process, and Negative regulation of telomere maintenance. Each is linked with PGGHG in more than 10 cancer types. Because this analysis shows association rather than direction, both PGGHG-to-partner and partner-to-PGGHG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein polyglycylation grouped by PGGHG-low versus PGGHG-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGGHG→partner) and Y-score (partner→PGGHG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein polyglycylation →	+1.390	+1.792	<.001	<.001	3	11
BONE	Pre-mRNA catabolic process →	+0.189	+1.446	<.001	<.001	3	11
BONE	Negative regulation of telomere maintenance →	+0.072	+1.523	<.001	<.001	3	10
URINARY_TRACT	Regulation of sphingolipid biosynthetic process →	+0.111	+1.773	<.001	<.001	3	10
OESOPHAGUS	Cilium-dependent cell motility →	-0.121	-2.451	<.001	<.001	3	10
BONE	Regulation of toll-like receptor signaling pathway →	+0.104	+2.077	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,224 associations by consensus.

Protein polyglycylation by PGGHG expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →