PGF

Across TCGA patient cohorts, PGF protein abundance is significantly associated with the RNA expression of many other genes, with 1,650 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PGF-associated genes across cancer lineages are ASAH1, NR3C1, and FAM162A. Each is linked with PGF in more than 1 cancer types. Because this analysis shows association rather than direction, both PGF-to-partner and partner-to-PGF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGF versus ASAH1 in CCRCC, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGF→partner) and Y-score (partner→PGF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ASAH1 →	-0.701	-2.013	<.001	.002	3	1
CCRCC	NR3C1 →	+0.680	+1.469	<.001	<.001	3	1
CCRCC	FAM162A →	+0.728	+1.541	.008	.004	3	1
CCRCC	VAX2 →	+0.564	+1.576	.009	.004	3	1
CCRCC	PTPA →	+0.521	+1.287	.004	.004	3	1
CCRCC	IFIT3 →	+0.792	+1.606	.006	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,650 associations by consensus.

PGF vs ASAH1 — CCRCC

Explore this scatter interactively →