PGDP1

Across TCGA pan-cancer cohorts, PGDP1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated PGDP1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher PGDP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PGDP1 expression acts as an unfavorable survival marker, although some lineages such as LUSC and SKCM show a favorable association.

ACC, LUSC, and LUAD are the cancer types where PGDP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.173	0.639	.001	58	view →
LUSC	OS	Quartile	II,III,IV	0.842	0.652	.003	48	view →
LUAD	OS	Tertile	All	0.748	0.862	.001	44	view →
SKCM	OS	Tertile	All	0.428	0.274	.003	36	view →
KIRC	DFS	Quartile	All	0.556	0.678	.012	35	view →
READ	OS	Median	All	1.000	0.820	.007	34	view →
UVM	OS	Median	III,IV	0.625	0.945	.001	31	view →
LGG	DFS	Quartile	All	0.645	0.805	<.001	24	view →
BRCA	OS	Tertile	IV	0.429	0.833	.002	22	view →
KICH	DFS	Median	III,IV	0.379	0.919	.008	19	view →
UCS	DFS	Median	III,IV	0.278	0.563	.018	18	view →
THCA	OS	Median	II,III,IV	0.927	1.000	.008	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

PGDP1–ACC (DFS)

Open the ACC breakdown →