PGC

Across TCGA patient cohorts, PGC RNA expression is significantly associated with the protein abundance of many other proteins, with 12,647 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PGC-associated proteins across cancer lineages are TPI1_S80, UNC13B, and UTRN_S2223. Each is linked with PGC in more than 3 cancer types. Because this analysis shows association rather than direction, both PGC-to-partner and partner-to-PGC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGC versus TPI1_S80 in LUAD, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PGC→partner) and Y-score (partner→PGC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TPI1_S80 →	-0.637	-3.091	<.001	<.001	3	3
LUAD	UNC13B →	+0.357	+1.994	<.001	<.001	3	3
LSCC	UTRN_S2223 →	+0.533	+1.915	<.001	<.001	3	3
LUAD	ZMYND11_S403 →	+0.446	+2.544	.001	<.001	3	3
LUAD	SPC25 →	-0.524	-2.716	.003	.002	3	3
LUAD	ARHGEF37 →	+0.303	+1.932	.002	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,647 associations by consensus.

PGC vs TPI1_S80 — LUAD

Explore this scatter interactively →