Across TCGA pan-cancer cohorts, PGBP RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of PGBP’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where PGBP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PGBP is over-expressed in tumor, although a few such as ESCA show the opposite, repressed pattern.

KIRC and ESCA are the cancer types where PGBP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PGBP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.033	<.001	11	view →
ESCA	All	All	−0.846	.015	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: PGBP RNA expression & survival · all PGBP data types