PGBD4P4

Across TCGA pan-cancer cohorts, PGBD4P4 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated PGBD4P4 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PGBD4P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PGBD4P4 expression acts as an unfavorable survival marker.

HNSC, STAD, and LUAD are the cancer types where PGBD4P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.182	0.744	<.001	108	view →
STAD	OS	Tertile	All	0.291	0.596	<.001	90	view →
LUAD	OS	Tertile	II,III,IV	0.155	0.682	<.001	45	view →
LGG	DFS	Tertile	All	0.259	0.760	<.001	36	view →
KIRC	OS	Tertile	II,III,IV	0.173	0.558	.008	30	view →
THYM	DFS	Tertile	All	0.174	0.759	.028	27	view →
UCEC	OS	Tertile	IV	0.231	0.592	.036	18	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

PGBD4P4–HNSC (OS)

Open the HNSC breakdown →