PGBD3

Across TCGA patient cohorts, PGBD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,479 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible PGBD3-associated GO terms across cancer lineages are Double-strand break repair via classical nonhomologous end joining, Protein desumoylation, and Obsolete mRNA polyadenylation. Each is linked with PGBD3 in more than 21 cancer types. Because this analysis shows association rather than direction, both PGBD3-to-partner and partner-to-PGBD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Double-strand break repair via classical nonhomologous end joining grouped by PGBD3-low versus PGBD3-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGBD3→partner) and Y-score (partner→PGBD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Double-strand break repair via classical nonhomologous end joining →	+0.063	+0.430	.001	<.001	3	22
UVM	Protein desumoylation →	+0.054	+0.032	<.001	<.001	3	19
UVM	Obsolete mRNA polyadenylation →	+0.042	+0.032	<.001	<.001	3	18
ESCA	Single strand break repair →	+0.032	+0.080	.002	<.001	3	18
TGCT	Non-motile cilium assembly →	+0.027	+0.064	<.001	<.001	2	18
UVM	snRNA metabolic process →	+0.037	+0.038	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,479 associations by consensus.

Double-strand break repair via classical nonhomologous end joining by PGBD3 expression — SCLC

Explore this box plot interactively →