Across TCGA patient cohorts, PGBD2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,351 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PGBD2-associated genes across cancer lineages are OGFOD2, ACSBG2, and CHST12. Each is linked with PGBD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PGBD2-to-partner and partner-to-PGBD2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGBD2→partner) and Y-score (partner→PGBD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	OGFOD2 →	+0.412	+0.863	.001	.004	3	2
GBM	ACSBG2 →	+0.524	+0.617	.001	.006	3	2
GBM	CHST12 →	+0.434	+0.714	<.001	.001	3	2
BRCA	DPH7 →	+0.530	+1.107	.003	<.001	3	2
GBM	C2orf68 →	+0.547	+0.996	<.001	<.001	3	2
GBM	LRRC28 →	+0.358	+0.991	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,351 associations by consensus.

Exploration

PGBD2 survival (RNA) · tumor vs normal (RNA) · all PGBD2 data types