Across TCGA patient cohorts, PGBD2 mutation is significantly associated with the RNA expression of many other genes, with 3,740 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PGBD2-associated genes across cancer lineages are MIR4690, RNU6-236P, and RNU6-73P. Each is linked with PGBD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PGBD2-to-partner and partner-to-PGBD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGBD2→partner) and Y-score (partner→PGBD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	MIR4690 →	+0.815	+5.450	<.001	.004	3	3
LIHC	RNU6-236P →	+0.253	+5.149	<.001	.003	3	2
LIHC	RNU6-73P →	+0.237	+4.647	<.001	.007	3	2
UCEC	CBARP →	+0.616	+2.896	<.001	<.001	3	2
LUAD	C16orf90 →	+0.152	+3.217	.005	.009	3	2
UCEC	ACTR5 →	+0.276	+1.752	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,740 associations by consensus.

Exploration

PGBD2 survival (RNA) · tumor vs normal (RNA) · all PGBD2 data types