Across TCGA cell cohorts, PGBD2 mutation is significantly associated with the RNA expression of many other genes, with 88 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PGBD2-associated genes across cancer lineages are SERPINA7, C1orf158, and CCL16. Each is linked with PGBD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PGBD2-to-partner and partner-to-PGBD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGBD2→partner) and Y-score (partner→PGBD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	SERPINA7 →	+0.459	+4.807	<.001	.006	3	1
BLOOD_Myeloma	C1orf158 →	+0.053	+4.807	<.001	.006	3	1
BLOOD_Myeloma	CCL16 →	+0.030	+4.807	<.001	.006	3	1
LARGE_INTESTINE	POLDIP3 →	+0.784	+3.192	<.001	.007	3	1
LARGE_INTESTINE	TNRC6B →	+0.924	+3.064	<.001	.009	3	1
LARGE_INTESTINE	PPP2R5D →	+0.835	+3.064	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

Exploration

PGBD2 survival (RNA) · tumor vs normal (RNA) · all PGBD2 data types