PGBD1

Across TCGA patient cohorts, PGBD1 protein abundance is significantly associated with the protein abundance of many other proteins, with 3,493 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PGBD1-associated proteins across cancer lineages are NRBP1_S53, TTC25, and CASKIN1_S694. Each is linked with PGBD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PGBD1-to-partner and partner-to-PGBD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGBD1 versus NRBP1_S53 in GBM, with a Pearson correlation of 0.53.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PGBD1→partner) and Y-score (partner→PGBD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NRBP1_S53 →	+0.380	+0.379	.002	<.001	2	1
GBM	TTC25 →	+0.583	+0.296	.009	.008	1	1
GBM	CASKIN1_S694 →	-1.331	-0.349	.001	.003	1	1
GBM	DACT3_S426 →	-1.175	-0.349	.008	.003	1	1
GBM	EEPD1_T134 →	-1.016	-0.349	.003	.003	1	1
GBM	EIF4ENIF1_S345 →	-0.410	-0.296	.002	.008	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,493 associations by consensus.

PGBD1 vs NRBP1_S53 — GBM

Explore this scatter interactively →