PGBD1

Across TCGA cell cohorts, PGBD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,923 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PGBD1-associated GO terms across cancer lineages are Positive regulation of organelle assembly, Microtubule cytoskeleton organization involved in mitosis, and Positive regulation of cell cycle. Each is linked with PGBD1 in more than 16 cancer types. Because this analysis shows association rather than direction, both PGBD1-to-partner and partner-to-PGBD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of organelle assembly grouped by PGBD1-low versus PGBD1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGBD1→partner) and Y-score (partner→PGBD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of organelle assembly →	+0.056	+1.136	.001	.001	3	17
URINARY_TRACT	Microtubule cytoskeleton organization involved in mitosis →	+0.104	+1.248	<.001	.002	3	16
STOMACH	Positive regulation of cell cycle →	+0.072	+1.430	.001	.001	3	16
PANCREAS	Positive regulation of cell cycle process →	+0.087	+0.773	<.001	<.001	3	16
LUNG_SCLC	Negative regulation of cell cycle process →	+0.065	+0.959	<.001	<.001	3	15
URINARY_TRACT	Regulation of chromosome organization →	+0.100	+1.355	<.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,923 associations by consensus.

Positive regulation of organelle assembly by PGBD1 expression — STOMACH

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