PGAP4

Across TCGA patient cohorts, PGAP4 protein abundance is significantly associated with the RNA expression of many other genes, with 7,849 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PGAP4-associated genes across cancer lineages are APCDD1L-DT, NBPF14, and COX6A1. Each is linked with PGAP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both PGAP4-to-partner and partner-to-PGAP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGAP4 versus APCDD1L-DT in PDAC, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGAP4→partner) and Y-score (partner→PGAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	APCDD1L-DT →	-0.918	-0.605	.008	.009	3	3
GBM	NBPF14 →	-0.553	-0.692	<.001	.002	3	3
UCEC	COX6A1 →	+1.509	+1.373	.005	.004	3	3
LSCC	NQO1 →	+1.828	+0.601	<.001	.008	3	3
UCEC	KLRG2 →	+1.410	+1.373	.003	.004	3	3
GBM	IGDCC4 →	-0.885	-0.792	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,849 associations by consensus.

PGAP4 vs APCDD1L-DT — PDAC

Explore this scatter interactively →