PGAP4

Across TCGA cell cohorts, PGAP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,995 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PGAP4-associated GO terms across cancer lineages are RNA surveillance, Aerobic electron transport chain, and Regulation of myoblast fusion. Each is linked with PGAP4 in more than 7 cancer types. Because this analysis shows association rather than direction, both PGAP4-to-partner and partner-to-PGAP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA surveillance grouped by PGAP4-low versus PGAP4-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGAP4→partner) and Y-score (partner→PGAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	RNA surveillance →	+0.062	+0.964	<.001	.009	3	8
LUNG_NSCLC_LUSC	Aerobic electron transport chain →	+0.088	+2.522	.009	<.001	3	8
BLOOD_Leukemia	Regulation of myoblast fusion →	+0.058	+1.672	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Respiratory electron transport chain →	+0.079	+1.973	<.001	<.001	3	7
BLOOD_Leukemia	Negative regulation of myoblast fusion →	+0.065	+1.408	<.001	<.001	3	7
BLOOD_Leukemia	Cytoplasmic translation →	+0.041	+1.012	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,995 associations by consensus.

RNA surveillance by PGAP4 expression — BREAST

Explore this box plot interactively →