Across TCGA patient cohorts, PGAP1 mutation is significantly associated with the RNA expression of many other genes, with 4,692 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PGAP1-associated genes across cancer lineages are CCL3, ATP5F1A, and PGBD4P2. Each is linked with PGAP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PGAP1-to-partner and partner-to-PGAP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGAP1→partner) and Y-score (partner→PGAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCL3 →	+0.580	+1.376	<.001	.001	3	3
UCEC	ATP5F1A →	+0.450	+1.680	<.001	<.001	3	3
READ	PGBD4P2 →	+0.198	+6.842	<.001	<.001	3	3
UCEC	TRAPPC4 →	+0.431	+2.082	<.001	<.001	3	3
UCEC	FCGR3A →	+0.663	+1.592	.001	.002	3	3
UCEC	RNU6-1213P →	+0.094	+2.484	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,692 associations by consensus.

Exploration

PGAP1 survival (RNA) · tumor vs normal (RNA) · all PGAP1 data types