Across TCGA cell cohorts, PGAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,217 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PGAP1-associated GO terms across cancer lineages are mRNA destabilization, Cytoskeleton-dependent intracellular transport, and Positive regulation of double-strand break repair. Each is linked with PGAP1 in more than 14 cancer types. Because this analysis shows association rather than direction, both PGAP1-to-partner and partner-to-PGAP1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGAP1→partner) and Y-score (partner→PGAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	mRNA destabilization →	+0.061	+1.050	<.001	<.001	3	15
STOMACH	Cytoskeleton-dependent intracellular transport →	+0.075	+1.693	<.001	<.001	3	14
OESOPHAGUS	Positive regulation of double-strand break repair →	+0.090	+1.576	<.001	.001	3	14
LUNG_NSCLC_LUSC	5S class rRNA transcription by RNA polymerase III →	+0.146	+1.047	.002	.003	2	15
SOFT_TISSUE	RNA destabilization →	+0.057	+1.080	.001	<.001	3	14
URINARY_TRACT	Regulation of mRNA catabolic process →	+0.062	+1.074	<.001	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,217 associations by consensus.

Exploration

PGAP1 survival (RNA) · tumor vs normal (RNA) · all PGAP1 data types