PGAM5P1

Across TCGA patient cohorts, PGAM5P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,053 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PGAM5P1-associated GO terms across cancer lineages are Protein localization to cytoplasmic stress granule, Positive regulation of intracellular transport, and Regulation of post-translational protein modification. Each is linked with PGAM5P1 in more than 11 cancer types. Because this analysis shows association rather than direction, both PGAM5P1-to-partner and partner-to-PGAM5P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cytoplasmic stress granule grouped by PGAM5P1-low versus PGAM5P1-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGAM5P1→partner) and Y-score (partner→PGAM5P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	Protein localization to cytoplasmic stress granule →	+0.075	+0.093	<.001	.002	3	12
STAD	Positive regulation of intracellular transport →	+0.057	+0.028	<.001	<.001	3	12
ESCA	Regulation of post-translational protein modification →	+0.074	+0.056	<.001	<.001	3	11
ESCA	Protein stabilization →	+0.065	+0.071	<.001	<.001	3	11
ESCA	Regulation of DNA repair →	+0.069	+0.064	<.001	<.001	3	11
ESCA	Double-strand break repair via nonhomologous end joining →	+0.065	+0.030	<.001	.003	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,053 associations by consensus.

Protein localization to cytoplasmic stress granule by PGAM5P1 expression — UCS

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