PGAM4P2

Across TCGA pan-cancer cohorts, PGAM4P2 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated PGAM4P2 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PGAM4P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PGAM4P2 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

LUAD, OV, and KIRC are the cancer types where PGAM4P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	II,III,IV	0.300	0.715	<.001	108	view →
OV	OS	Tertile	All	0.489	0.850	<.001	108	view →
KIRC	OS	Tertile	All	0.727	0.823	.002	96	view →
HNSC	DFS	Tertile	All	0.853	0.681	.004	48	view →
STAD	DFS	Tertile	II,III,IV	0.340	0.562	.014	42	view →
CESC	OS	Tertile	IV	0.121	0.591	.029	36	view →
SARC	OS	Tertile	All	0.482	0.845	.004	36	view →
LUSC	OS	Tertile	III,IV	0.524	0.684	.001	21	view →
PAAD	OS	Tertile	II,III,IV	0.392	0.566	.012	18	view →
BLCA	OS	Tertile	IV	0.076	0.605	<.001	18	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
LIHC	DFS	Tertile	All	0.110	0.530	.008	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

PGAM4P2–LUAD (OS)

Open the LUAD breakdown →