Across TCGA patient cohorts, PGAM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 596 significant associations in total. SCLC shows the largest number of these associations.

The most reproducible PGAM2-associated GO terms across cancer lineages are Spontaneous neurotransmitter secretion, CGMP biosynthetic process, and Indolalkylamine metabolic process. Each is linked with PGAM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PGAM2-to-partner and partner-to-PGAM2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGAM2→partner) and Y-score (partner→PGAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Spontaneous neurotransmitter secretion →	+0.644	+0.933	.002	.001	3	1
SCLC	CGMP biosynthetic process →	+1.143	+1.475	<.001	<.001	3	1
SCLC	Indolalkylamine metabolic process →	-0.637	-1.560	<.001	<.001	3	1
SCLC	Potassium ion transport →	+0.039	+1.380	<.001	.001	3	1
SCLC	Iron ion transport →	+0.084	+1.515	<.001	<.001	3	1
SCLC	Neurotransmitter transport →	+0.060	+1.059	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 596 associations by consensus.

Exploration

PGAM2 survival (RNA) · tumor vs normal (RNA) · all PGAM2 data types