PGAM1P12

Across TCGA pan-cancer cohorts, PGAM1P12 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of PGAM1P12’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where PGAM1P12 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PGAM1P12 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

COAD, KIRC, and THCA are the cancer types where PGAM1P12 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PGAM1P12 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.049	.044	2	view →
KIRC	Male	IV	−0.046	.002	2	view →
THCA	Female	II,III,IV	−0.029	.036	1	view →
LUSC	All	All	+0.025	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

PGAM1P12–COAD

Open the COAD breakdown →