PGAM1P11

Across TCGA pan-cancer cohorts, PGAM1P11 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated PGAM1P11 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher PGAM1P11 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PGAM1P11 expression acts as an unfavorable survival marker, although some lineages such as KIRP and HNSC show a favorable association.

KIRP, HNSC, and STAD are the cancer types where PGAM1P11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	II,III,IV	0.741	0.297	<.001	83	view →
HNSC	DFS	Quartile	II,III,IV	0.441	0.232	.004	65	view →
STAD	OS	Median	III,IV	0.693	0.304	.001	48	view →
ACC	DFS	Quartile	All	0.306	0.635	<.001	37	view →
THYM	OS	Median	II,III,IV	0.876	1.000	.005	29	view →
COAD	OS	Median	All	0.510	0.801	.004	20	view →
LGG	DFS	Tertile	All	0.757	0.859	<.001	18	view →
DLBC	DFS	Tertile	II,III,IV	0.196	0.827	.014	16	view →
LUSC	OS	Median	II,III,IV	0.476	0.326	.018	16	view →
READ	OS	Tertile	III,IV	0.778	0.267	.019	10	view →
THCA	OS	Median	All	0.999	0.980	.007	10	view →
UVM	DFS	Median	III,IV	0.229	0.657	.031	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

PGAM1P11–KIRP (DFS)

Open the KIRP breakdown →