Across TCGA pan-cancer cohorts, PFN1P4 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated PFN1P4 data layer.
The strongest signal is observed in kidney chromophobe (KICH), where higher PFN1P4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PFN1P4 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.
KICH, STAD, and HNSC are the cancer types where PFN1P4 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.