PFKFB3

Across TCGA cell cohorts, PFKFB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,874 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PFKFB3-associated GO terms across cancer lineages are Glycolytic process, Purine nucleoside diphosphate catabolic process, and Purine ribonucleoside diphosphate catabolic process. Each is linked with PFKFB3 in more than 14 cancer types. Because this analysis shows association rather than direction, both PFKFB3-to-partner and partner-to-PFKFB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycolytic process grouped by PFKFB3-low versus PFKFB3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PFKFB3→partner) and Y-score (partner→PFKFB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Glycolytic process →	+0.117	+1.363	.001	<.001	3	15
OVARY	Purine nucleoside diphosphate catabolic process →	+0.107	+1.376	.002	.001	3	14
OVARY	Purine ribonucleoside diphosphate catabolic process →	+0.107	+1.376	.002	.001	3	14
OVARY	Ribonucleoside diphosphate catabolic process →	+0.113	+1.342	.001	.002	3	13
SKIN	Nucleoside diphosphate catabolic process →	+0.100	+1.031	<.001	<.001	3	13
OVARY	Pyridine nucleotide catabolic process →	+0.122	+1.248	.003	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,874 associations by consensus.

Glycolytic process by PFKFB3 expression — OVARY

Explore this box plot interactively →