Across TCGA patient cohorts, PFDN6 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,109 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PFDN6-associated proteins across cancer lineages are SRPK1, DAXX, and ABCF1. Each is linked with PFDN6 in more than 7 cancer types. Because this analysis shows association rather than direction, both PFDN6-to-partner and partner-to-PFDN6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PFDN6→partner) and Y-score (partner→PFDN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SRPK1 →	+0.471	+0.618	<.001	<.001	3	8
LSCC	DAXX →	+0.334	+0.437	<.001	<.001	3	8
LSCC	ABCF1 →	+0.309	+0.550	<.001	<.001	3	7
LSCC	GNL1 →	+0.297	+0.513	<.001	<.001	3	7
GBM	MCM5 →	+0.653	+0.259	<.001	<.001	3	7
LSCC	XPO5 →	+0.579	+0.566	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,109 associations by consensus.

Exploration

PFDN6 survival (RNA) · tumor vs normal (RNA) · all PFDN6 data types