Across TCGA patient cohorts, PFDN6 protein abundance is significantly associated with the RNA expression of many other genes, with 11,870 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PFDN6-associated genes across cancer lineages are PFDN4, CSTF1, and ACOT8. Each is linked with PFDN6 in more than 6 cancer types. Because this analysis shows association rather than direction, both PFDN6-to-partner and partner-to-PFDN6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PFDN6→partner) and Y-score (partner→PFDN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PFDN4 →	+0.704	+0.222	<.001	<.001	3	7
LSCC	CSTF1 →	+0.412	+0.211	<.001	<.001	3	6
COAD	ACOT8 →	+0.465	+0.232	.003	.004	3	5
OV	ARHGAP9 →	-0.641	-0.198	.002	.003	3	5
LSCC	RAE1 →	+0.594	+0.227	<.001	<.001	3	5
LSCC	GID8 →	+0.489	+0.214	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,870 associations by consensus.

Exploration

PFDN6 survival (RNA) · tumor vs normal (RNA) · all PFDN6 data types