Across TCGA patient cohorts, PFDN6 mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible PFDN6-associated genes across cancer lineages are DEFB123, RN7SKP232, and LINC00708. Each is linked with PFDN6 in more than 1 cancer types. Because this analysis shows association rather than direction, both PFDN6-to-partner and partner-to-PFDN6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PFDN6→partner) and Y-score (partner→PFDN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	DEFB123 →	+0.122	+5.010	<.001	.009	3	1
CESC	RN7SKP232 →	+0.166	+5.539	<.001	.004	3	1
CESC	LINC00708 →	+0.056	+5.418	<.001	.005	3	1
BLCA	OR8A3P →	+0.126	+5.411	.003	.005	3	1
BLCA	LINC01570 →	+0.077	+5.038	<.001	.009	3	1
BLCA	NFILZ →	+0.111	+5.411	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Exploration

PFDN6 survival (RNA) · tumor vs normal (RNA) · all PFDN6 data types