PFDN4

Across TCGA patient cohorts, PFDN4 protein abundance is significantly associated with the RNA expression of many other genes, with 8,662 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PFDN4-associated genes across cancer lineages are RAD51AP1, MYBL2, and CDCA3. Each is linked with PFDN4 in more than 4 cancer types. Because this analysis shows association rather than direction, both PFDN4-to-partner and partner-to-PFDN4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PFDN4 versus RAD51AP1 in BRCA, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PFDN4→partner) and Y-score (partner→PFDN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RAD51AP1 →	+0.751	+0.307	.001	.001	3	5
LUAD	MYBL2 →	+1.249	+0.302	<.001	<.001	3	4
LSCC	CDCA3 →	+0.757	+0.222	<.001	.001	3	4
LSCC	FBXO5 →	+0.576	+0.178	.004	.009	3	4
LUAD	CENPA →	+0.952	+0.322	<.001	<.001	3	4
UCEC	CDC20 →	+1.257	+0.260	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,662 associations by consensus.

PFDN4 vs RAD51AP1 — BRCA

Explore this scatter interactively →