PFDN4

Across TCGA patient cohorts, PFDN4 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PFDN4-associated genes across cancer lineages are CLP, Epithelial cells, and Mesangial cells. Each is linked with PFDN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PFDN4-to-partner and partner-to-PFDN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLP grouped by PFDN4-low versus PFDN4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PFDN4→partner) and Y-score (partner→PFDN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CLP →	-0.069	-3.169	.046	.019	3	1
UCEC	Epithelial cells →	-0.125	-3.169	.001	.020	1	1
UCEC	Mesangial cells →	-0.055	-3.159	.010	.020	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CLP by PFDN4 expression — UCEC

Explore this box plot interactively →