PFDN1

Across TCGA cell cohorts, PFDN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,154 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PFDN1-associated GO terms across cancer lineages are Dendritic transport of messenger ribonucleoprotein complex, Protein depolymerization, and Regulation of CD8-positive, alpha-beta T cell extravasation. Each is linked with PFDN1 in more than 15 cancer types. Because this analysis shows association rather than direction, both PFDN1-to-partner and partner-to-PFDN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dendritic transport of messenger ribonucleoprotein complex grouped by PFDN1-low versus PFDN1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PFDN1→partner) and Y-score (partner→PFDN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Dendritic transport of messenger ribonucleoprotein complex →	-0.053	-0.673	<.001	<.001	3	16
SKIN	Protein depolymerization →	+0.104	+0.529	<.001	<.001	3	13
LUNG_SCLC	Regulation of CD8-positive, alpha-beta T cell extravasation →	+0.534	+0.802	.003	<.001	3	11
STOMACH	Metaphase/anaphase transition of cell cycle →	+0.143	+1.090	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of chromosome segregation →	+0.114	+1.065	<.001	<.001	3	11
URINARY_TRACT	Microtubule polymerization or depolymerization →	+0.102	+0.903	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,154 associations by consensus.

Dendritic transport of messenger ribonucleoprotein complex by PFDN1 expression — LUNG_SCLC

Explore this box plot interactively →