PF4V1

Across TCGA patient cohorts, PF4V1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,182 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PF4V1-associated genes across cancer lineages are PCTP, PF4, and TRIM61. Each is linked with PF4V1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PF4V1-to-partner and partner-to-PF4V1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PF4V1 versus PCTP in OV, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PF4V1→partner) and Y-score (partner→PF4V1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PCTP →	-1.116	-0.646	.002	.009	3	2
LSCC	PF4 →	+0.571	+1.062	.002	.002	3	2
LUAD	TRIM61 →	-0.576	-0.676	.009	.004	3	2
LSCC	RNU6-1336P →	-1.512	-0.828	.001	.009	3	2
LSCC	RPS14P5 →	-1.226	-1.174	.001	<.001	3	2
HNSC	H2BP2 →	-0.355	-0.801	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,182 associations by consensus.

PF4V1 vs PCTP — OV

Explore this scatter interactively →